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Single-nucleus transcriptome analysis reveals dysregulation of angiogenic endothelial cells and neuroprotective glia in Alzheimer’s disease

Alzheimer’s disease (AD) is the most common form of dementia but has no effective treatment. A comprehensive investigation of cell type-specific responses and cellular heterogeneity in AD is required to provide precise molecular and cellular targets for therapeutic development. Accordingly, we perfo...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Lau, Shun-Fat, Cao, Han, Fu, Amy K. Y., Ip, Nancy Y.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568283/
https://ncbi.nlm.nih.gov/pubmed/32989152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2008762117
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