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Cytokine signaling convergence regulates the microglial state transition in Alzheimer’s disease

Genetic analyses have revealed the pivotal contribution of microglial dysfunctions to the pathogenesis of Alzheimer’s disease (AD). Along AD progression, the accumulation of danger-associated molecular patterns (DAMPs) including beta-amyloid and hyperphosphorylated tau continuously stimulates microg...

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Bibliografiske detaljer
Udgivet i:Cell Mol Life Sci
Main Authors: Lau, Shun-Fat, Fu, Amy K. Y., Ip, Nancy Y.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8195901/
https://ncbi.nlm.nih.gov/pubmed/33847763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-021-03810-0
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