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Cytokine signaling convergence regulates the microglial state transition in Alzheimer’s disease

Genetic analyses have revealed the pivotal contribution of microglial dysfunctions to the pathogenesis of Alzheimer’s disease (AD). Along AD progression, the accumulation of danger-associated molecular patterns (DAMPs) including beta-amyloid and hyperphosphorylated tau continuously stimulates microg...

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Détails bibliographiques
Publié dans:Cell Mol Life Sci
Auteurs principaux: Lau, Shun-Fat, Fu, Amy K. Y., Ip, Nancy Y.
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8195901/
https://ncbi.nlm.nih.gov/pubmed/33847763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-021-03810-0
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