Retinoic acid signaling is critical during the totipotency window in early mammalian development

Totipotent cells hold enormous potential for regenerative medicine. Thus, the development of cellular models recapitulating totipotent-like features is of paramount importance. Cells resembling the totipotent cells of early embryos arise spontaneously in mouse embryonic stem (ES) cell cultures. Such...

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Publicat a:Nat Struct Mol Biol
Autors principals: Iturbide, Ane, Ruiz Tejada Segura, Mayra L., Noll, Camille, Schorpp, Kenji, Rothenaigner, Ina, Ruiz-Morales, Elias R., Lubatti, Gabriele, Agami, Ahmed, Hadian, Kamyar, Scialdone, Antonio, Torres-Padilla, Maria-Elena
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group US 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8195742/
https://ncbi.nlm.nih.gov/pubmed/34045724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-021-00590-w
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