Arginine recycling in endothelial cells is regulated BY HSP90 and the ubiquitin proteasome system

Despite the saturating concentrations of intracellular l-arginine, nitric oxide (NO) production in endothelial cells (EC) can be stimulated by exogenous arginine. This phenomenon, termed the “arginine paradox” led to the discovery of an arginine recycling pathway in which l-citrulline is recycled to...

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Detalhes bibliográficos
Publicado no:Nitric Oxide
Main Authors: Wu, Xiaomin, Sun, Xutong, Sharma, Shruti, Lu, Qing, Yegambaram, Manivannan, Hou, Yali, Wang, Ting, Fineman, Jeffrey R., Black, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8193791/
https://ncbi.nlm.nih.gov/pubmed/33338599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2020.12.003
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