Interplay between recombinant Hsp70 and proteasomes: proteasome activity modulation and ubiquitin-independent cleavage of Hsp70

The heat shock protein 70 (Hsp70, human HSPA1A) plays indispensable roles in cellular stress responses and protein quality control (PQC). In the framework of PQC, it cooperates with the ubiquitin-proteasome system (UPS) to clear damaged and dysfunctional proteins in the cell. Moreover, Hsp70 itself...

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Dades bibliogràfiques
Publicat a:Cell Stress Chaperones
Autors principals: Morozov, Alexey V., Astakhova, Tatiana M., Garbuz, David G., Krasnov, George S., Bobkova, Natalia V., Zatsepina, Olga G., Karpov, Vadim L., Evgen’ev, Michail B.
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2017
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573687/
https://ncbi.nlm.nih.gov/pubmed/28447215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0792-y
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