Interplay between recombinant Hsp70 and proteasomes: proteasome activity modulation and ubiquitin-independent cleavage of Hsp70

The heat shock protein 70 (Hsp70, human HSPA1A) plays indispensable roles in cellular stress responses and protein quality control (PQC). In the framework of PQC, it cooperates with the ubiquitin-proteasome system (UPS) to clear damaged and dysfunctional proteins in the cell. Moreover, Hsp70 itself...

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Bibliografski detalji
Izdano u:Cell Stress Chaperones
Glavni autori: Morozov, Alexey V., Astakhova, Tatiana M., Garbuz, David G., Krasnov, George S., Bobkova, Natalia V., Zatsepina, Olga G., Karpov, Vadim L., Evgen’ev, Michail B.
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2017
Teme:
Original Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573687/
https://ncbi.nlm.nih.gov/pubmed/28447215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0792-y
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