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Interplay between recombinant Hsp70 and proteasomes: proteasome activity modulation and ubiquitin-independent cleavage of Hsp70

The heat shock protein 70 (Hsp70, human HSPA1A) plays indispensable roles in cellular stress responses and protein quality control (PQC). In the framework of PQC, it cooperates with the ubiquitin-proteasome system (UPS) to clear damaged and dysfunctional proteins in the cell. Moreover, Hsp70 itself...

詳細記述

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書誌詳細
出版年:Cell Stress Chaperones
主要な著者: Morozov, Alexey V., Astakhova, Tatiana M., Garbuz, David G., Krasnov, George S., Bobkova, Natalia V., Zatsepina, Olga G., Karpov, Vadim L., Evgen’ev, Michail B.
フォーマット: Artigo
言語:Inglês
出版事項: Springer Netherlands 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573687/
https://ncbi.nlm.nih.gov/pubmed/28447215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0792-y
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