Exogenous Hsp70 delays senescence and improves cognitive function in aging mice

Molecular chaperone Heat Shock Protein 70 (Hsp70) plays an important protective role in various neurodegenerative disorders often associated with aging, but its activity and availability in neuronal tissue decrease with age. Here we explored the effects of intranasal administration of exogenous reco...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Bobkova, Natalia V., Evgen’ev, Mikhail, Garbuz, David G., Kulikov, Alexei M., Morozov, Alexei, Samokhin, Alexander, Velmeshev, Dmitri, Medvinskaya, Natalia, Nesterova, Inna, Pollock, Andrew, Nudler, Evgeny
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2015
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702952/
https://ncbi.nlm.nih.gov/pubmed/26668376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516131112
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