Exogenous Hsp70 delays senescence and improves cognitive function in aging mice

Molecular chaperone Heat Shock Protein 70 (Hsp70) plays an important protective role in various neurodegenerative disorders often associated with aging, but its activity and availability in neuronal tissue decrease with age. Here we explored the effects of intranasal administration of exogenous reco...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Bobkova, Natalia V., Evgen’ev, Mikhail, Garbuz, David G., Kulikov, Alexei M., Morozov, Alexei, Samokhin, Alexander, Velmeshev, Dmitri, Medvinskaya, Natalia, Nesterova, Inna, Pollock, Andrew, Nudler, Evgeny
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702952/
https://ncbi.nlm.nih.gov/pubmed/26668376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516131112
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