Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis

Profiling studies have revealed considerable phenotypic heterogeneity in cancer-associated fibroblasts (CAFs) present within the tumour microenvironment, however, functional characterisation of different CAF subsets is hampered by the lack of specific markers defining these populations. Here we show...

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Udgivet i:Nat Commun
Main Authors: Jungwirth, Ute, van Weverwijk, Antoinette, Evans, Rachel J., Jenkins, Liam, Vicente, David, Alexander, John, Gao, Qiong, Haider, Syed, Iravani, Marjan, Isacke, Clare M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192501/
https://ncbi.nlm.nih.gov/pubmed/34112782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23583-1
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