Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis

Tumour-associated fibroblasts (TAFs), as a functionally supportive microenvironment, play an essential role in tumour progression. Here we investigate the role of IL-25, an endogenous anticancer factor secreted from TAFs, in suppression of mouse 4T1 mammary tumour metastasis. We show that a syntheti...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yin, Shu-Yi, Jian, Feng-Yin, Chen, Yung-Hsiang, Chien, Shih-Chang, Hsieh, Mao-Chih, Hsiao, Pei-Wen, Lee, Wen-Hwa, Kuo, Yueh-Hsiung, Yang, Ning-Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837478/
https://ncbi.nlm.nih.gov/pubmed/27089063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11311
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