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The tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis
Inflammation and hypoxia are known to promote the metastatic progression of tumours. The CCAAT/enhancer-binding protein-δ (C/EBPδ, CEBPD) is an inflammatory response gene and candidate tumour suppressor, but its physiological role in tumourigenesis in vivo is unknown. Here, we demonstrate a tumour s...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018791/ https://ncbi.nlm.nih.gov/pubmed/21076392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.280 |
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