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The tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis

Inflammation and hypoxia are known to promote the metastatic progression of tumours. The CCAAT/enhancer-binding protein-δ (C/EBPδ, CEBPD) is an inflammatory response gene and candidate tumour suppressor, but its physiological role in tumourigenesis in vivo is unknown. Here, we demonstrate a tumour s...

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Bibliografiske detaljer
Main Authors: Balamurugan, Kuppusamy, Wang, Ju-Ming, Tsai, Hsin-Hwa, Sharan, Shikha, Anver, Miriam, Leighty, Robert, Sterneck, Esta
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018791/
https://ncbi.nlm.nih.gov/pubmed/21076392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.280
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