C/EBPδ targets cyclin D1 for proteasome-mediated degradation via induction of CDC27/APC3 expression

The transcription factor CCAAT/enhancer binding protein δ (C/EBPδ, CEBPD, NFIL-6β) has tumor suppressor function; however, the molecular mechanism(s) by which C/EBPδ exerts its effect are largely unknown. Here, we report that C/EBPδ induces expression of the Cdc27 (APC3) subunit of the anaphase prom...

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Detalhes bibliográficos
Main Authors: Pawar, Snehalata A., Sarkar, Tapasree Roy, Balamurugan, Kuppusamy, Sharan, Shikha, Wang, Jun, Zhang, Youhong, Dowdy, Steven F., Huang, A-Mei, Sterneck, Esta
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889124/
https://ncbi.nlm.nih.gov/pubmed/20439707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913813107
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