Pharmacological and Genetic Blockade of Trpm7 in the Carotid Body Treats Obesity-Induced Hypertension

Obesity increases levels of an adipocyte-produced hormone leptin, which activates the sympathetic nervous system leading to hypertension. We have recently reported that acute leptin infusion induces hypertension acting via the TRPM7 cation channel in the carotid bodies. We hypothesize that this mech...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Hypertension
Hauptverfasser: Shin, Mi-Kyung, Mitrut, Roxana, Gu, Chenjuan, Kim, Lenise J, Yeung, Bonnie H.Y., Lee, Rachel, Pham, Luu, Tang, Wan-Yee, Sham, James S. K., Cui, Honggang, Polotsky, Vsevolod Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192446/
https://ncbi.nlm.nih.gov/pubmed/33993722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.120.16527
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge