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Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis

RNA abundance is generally sensitive to perturbations in decay and synthesis rates, but crosstalk between RNA polymerase II transcription and cytoplasmic mRNA degradation often leads to compensatory changes in gene expression. Here, we reveal that widespread mRNA decay during early apoptosis repress...

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Udgivet i:eLife
Main Authors: Duncan-Lewis, Christopher, Hartenian, Ella, King, Valeria, Glaunsinger, Britt A
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192121/
https://ncbi.nlm.nih.gov/pubmed/34085923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58342
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