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Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis

RNA abundance is generally sensitive to perturbations in decay and synthesis rates, but crosstalk between RNA polymerase II transcription and cytoplasmic mRNA degradation often leads to compensatory changes in gene expression. Here, we reveal that widespread mRNA decay during early apoptosis repress...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Duncan-Lewis, Christopher, Hartenian, Ella, King, Valeria, Glaunsinger, Britt A
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192121/
https://ncbi.nlm.nih.gov/pubmed/34085923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58342
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