Changes in mRNA abundance drive shuttling of RNA binding proteins, linking cytoplasmic RNA degradation to transcription

Alterations in global mRNA decay broadly impact multiple stages of gene expression, although signals that connect these processes are incompletely defined. Here, we used tandem mass tag labeling coupled with mass spectrometry to reveal that changing the mRNA decay landscape, as frequently occurs dur...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:eLife
Main Authors: Gilbertson, Sarah, Federspiel, Joel D, Hartenian, Ella, Cristea, Ileana M, Glaunsinger, Britt
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2018
Teme:
Chromosomes and Gene Expression
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203436/
https://ncbi.nlm.nih.gov/pubmed/30281021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37663
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