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Changes in mRNA abundance drive shuttling of RNA binding proteins, linking cytoplasmic RNA degradation to transcription

Alterations in global mRNA decay broadly impact multiple stages of gene expression, although signals that connect these processes are incompletely defined. Here, we used tandem mass tag labeling coupled with mass spectrometry to reveal that changing the mRNA decay landscape, as frequently occurs dur...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: Gilbertson, Sarah, Federspiel, Joel D, Hartenian, Ella, Cristea, Ileana M, Glaunsinger, Britt
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6203436/
https://ncbi.nlm.nih.gov/pubmed/30281021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37663
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