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RNA decay during gammaherpesvirus infection reduces RNA polymerase II occupancy of host promoters but spares viral promoters

In mammalian cells, widespread acceleration of cytoplasmic mRNA degradation is linked to impaired RNA polymerase II (Pol II) transcription. This mRNA decay-induced transcriptional repression occurs during infection with gammaherpesviruses including Kaposi’s sarcoma-associated herpesvirus (KSHV) and...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Pathog
Egile Nagusiak: Hartenian, Ella, Gilbertson, Sarah, Federspiel, Joel D., Cristea, Ileana M., Glaunsinger, Britt A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032723/
https://ncbi.nlm.nih.gov/pubmed/32032393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008269
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