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Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis

RNA abundance is generally sensitive to perturbations in decay and synthesis rates, but crosstalk between RNA polymerase II transcription and cytoplasmic mRNA degradation often leads to compensatory changes in gene expression. Here, we reveal that widespread mRNA decay during early apoptosis repress...

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Podrobná bibliografie
Vydáno v:eLife
Hlavní autoři: Duncan-Lewis, Christopher, Hartenian, Ella, King, Valeria, Glaunsinger, Britt A
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8192121/
https://ncbi.nlm.nih.gov/pubmed/34085923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58342
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