Crystal structure of parallel G-quadruplex formed by the two-repeat ALS- and FTD-related GGGGCC sequence

The hexanucleotide repeat expansion, GGGGCC (G4C2), within the first intron of the C9orf72 gene is known to be the most common genetic cause of both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The G4C2 repeat expansions, either DNA or RNA, are able to form G-quadruplexes w...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Geng, Yanyan, Liu, Changdong, Cai, Qixu, Luo, Zhipu, Miao, Haitao, Shi, Xiao, Xu, Naining, Fung, Chun Po, Choy, To To, Yan, Bing, Li, Ning, Qian, Peiyuan, Zhou, Bo, Zhu, Guang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2021
Konular:
Structural Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191786/
https://ncbi.nlm.nih.gov/pubmed/34048588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab302
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