The crystal structure of an antiparallel chair-type G-quadruplex formed by Bromo-substituted human telomeric DNA

Human telomeric guanine-rich DNA, which could adopt different G-quadruplex structures, plays important roles in protecting the cell from recombination and degradation. Although many of these structures were determined, the chair-type G-quadruplex structure remains elusive. Here, we present a crystal...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Geng, Yanyan, Liu, Changdong, Zhou, Bo, Cai, Qixu, Miao, Haitao, Shi, Xiao, Xu, Naining, You, Yingying, Fung, Chun Po, Din, Rahman Ud, Zhu, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547763/
https://ncbi.nlm.nih.gov/pubmed/30957851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz221
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