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PIP(2) regulation of TRPC5 channel activation and desensitization

Transient receptor potential canonical type 5 (TRPC5) ion channels are expressed in the brain and kidney and have been identified as promising therapeutic targets whose selective inhibition can protect against diseases driven by a leaky kidney filter, such as focal segmental glomerular sclerosis. TR...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ningoo, Mehek, Plant, Leigh D., Greka, Anna, Logothetis, Diomedes E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8191310/
https://ncbi.nlm.nih.gov/pubmed/33933453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100726
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