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Antagonistic Regulation of Actin Dynamics and Cell Motility by TRPC5 and TRPC6 Channels

The Rho family of small guanosine triphosphatases (Rho GTPases: RhoA, Cdc42, and Rac1) regulates many aspects of cell behavior, including actin dynamics and cell migration. The generation of calcium ion (Ca(2+)) microdomains is critical in promoting cell migration because they control the localized...

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Bibliographische Detailangaben
Hauptverfasser: Tian, Dequan, Jacobo, Sarah M. P., Billing, David, Rozkalne, Anete, Gage, Steven D., Anagnostou, Theodora, Pavenstädt, Hermann, Hsu, Hsiang-Hao, Schlondorff, Johannes, Ramos, Arnolt, Greka, Anna
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071756/
https://ncbi.nlm.nih.gov/pubmed/20978238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2001200
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