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Translation and codon usage regulate Argonaute slicer activity to trigger small RNA biogenesis
In the Caenorhabditis elegans germline, thousands of mRNAs are concomitantly expressed with antisense 22G-RNAs, which are loaded into the Argonaute CSR-1. Despite their essential functions for animal fertility and embryonic development, how CSR-1 22G-RNAs are produced remains unknown. Here, we show...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8190271/ https://ncbi.nlm.nih.gov/pubmed/34108460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23615-w |
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