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Allosteric conformational ensembles have unlimited capacity for integrating information
Integration of binding information by macromolecular entities is fundamental to cellular functionality. Recent work has shown that such integration cannot be explained by pairwise cooperativities, in which binding is modulated by binding at another site. Higher-order cooperativities (HOCs), in which...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8189718/ https://ncbi.nlm.nih.gov/pubmed/34106049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65498 |
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