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Negative reciprocity, not ordered assembly, underlies the interaction of Sox2 and Oct4 on DNA

The mode of interaction of transcription factors (TFs) on eukaryotic genomes remains a matter of debate. Single-molecule data in living cells for the TFs Sox2 and Oct4 were previously interpreted as evidence of ordered assembly on DNA. However, the quantity that was calculated does not determine bin...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Biddle, John W, Nguyen, Maximilian, Gunawardena, Jeremy
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375704/
https://ncbi.nlm.nih.gov/pubmed/30762521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41017
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