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Negative reciprocity, not ordered assembly, underlies the interaction of Sox2 and Oct4 on DNA

The mode of interaction of transcription factors (TFs) on eukaryotic genomes remains a matter of debate. Single-molecule data in living cells for the TFs Sox2 and Oct4 were previously interpreted as evidence of ordered assembly on DNA. However, the quantity that was calculated does not determine bin...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Biddle, John W, Nguyen, Maximilian, Gunawardena, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6375704/
https://ncbi.nlm.nih.gov/pubmed/30762521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41017
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