Transcription shapes DNA replication initiation to preserve genome integrity

BACKGROUND: Early DNA replication occurs within actively transcribed chromatin compartments in mammalian cells, raising the immediate question of how early DNA replication coordinates with transcription to avoid collisions and DNA damage. RESULTS: We develop a high-throughput nucleoside analog incor...

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Gepubliceerd in:Genome Biol
Hoofdauteurs: Liu, Yang, Ai, Chen, Gan, Tingting, Wu, Jinchun, Jiang, Yongpeng, Liu, Xuhao, Lu, Rusen, Gao, Ning, Li, Qing, Ji, Xiong, Hu, Jiazhi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8188667/
https://ncbi.nlm.nih.gov/pubmed/34108027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-021-02390-3
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