Transcription shapes DNA replication initiation to preserve genome integrity

BACKGROUND: Early DNA replication occurs within actively transcribed chromatin compartments in mammalian cells, raising the immediate question of how early DNA replication coordinates with transcription to avoid collisions and DNA damage. RESULTS: We develop a high-throughput nucleoside analog incor...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Liu, Yang, Ai, Chen, Gan, Tingting, Wu, Jinchun, Jiang, Yongpeng, Liu, Xuhao, Lu, Rusen, Gao, Ning, Li, Qing, Ji, Xiong, Hu, Jiazhi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8188667/
https://ncbi.nlm.nih.gov/pubmed/34108027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-021-02390-3
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