PBPK model reporting template for chemical risk assessment applications

Physiologically-based pharmacokinetic (PBPK) modeling analysis does not stand on its own for regulatory purposes but is a robust tool to support drug/chemical safety assessment. While the development of PBPK models have grown steadily since their emergence, only a handful of models have been accepte...

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Detalhes bibliográficos
Publicado no:Regul Toxicol Pharmacol
Main Authors: Tan, Yu-Mei, Chan, Melissa, Chukwudebe, Amechi, Domoradzki, Jeanne, Fisher, Jeffrey, Hack, C. Eric, Hinderliter, Paul, Hirasawa, Kota, Leonard, Jeremy, Lumen, Annie, Paini, Alicia, Qian, Hua, Ruiz, Patricia, Wambaugh, John, Zhang, Fagen, Embry, Michelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8188465/
https://ncbi.nlm.nih.gov/pubmed/32502513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yrtph.2020.104691
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