PBPK Model for Atrazine and Its Chlorotriazine Metabolites in Rat and Human

The previously-published physiologically based pharmacokinetic model for atrazine (ATZ), deisopropylatrazine (DIA), deethylatrazine (DEA), and diaminochlorotriazine (DACT), which collectively comprise the total chlorotriazines (TCT) as represented in this study, was modified to allow for scaling to...

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Bibliografski detalji
Izdano u:Toxicol Sci
Glavni autori: Campbell, Jerry L., Andersen, Melvin E., Hinderliter, Paul M., Yi, Kun Don, Pastoor, Timothy P., Breckenridge, Charles B., Clewell, Harvey J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
Teme:
Pharmacokinetic Modeling of Atrazine and Metabolites
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809456/
https://ncbi.nlm.nih.gov/pubmed/26794140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw014
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