C9orf72-associated arginine-rich dipeptide repeats induce RNA-dependent nuclear accumulation of Staufen in neurons

RNA-binding proteins (RBPs) play essential roles in diverse cellular processes through post-transcriptional regulation of RNAs. The subcellular localization of RBPs is thus under tight control, the breakdown of which is associated with aberrant cytoplasmic accumulation of nuclear RBPs such as TDP-43...

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Veröffentlicht in:Hum Mol Genet
Hauptverfasser: Kim, Eun Seon, Chung, Chang Geon, Park, Jeong Hyang, Ko, Byung Su, Park, Sung Soon, Kim, Yoon Ha, Cha, In Jun, Kim, Jaekwang, Ha, Chang Man, Kim, Hyung-Jun, Lee, Sung Bae
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
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General Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8188407/
https://ncbi.nlm.nih.gov/pubmed/33783499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddab089
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