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Development of Agonist-Based PROTACs Targeting Liver X Receptor
Liver X receptors (LXRs) belong to the nuclear hormone receptor superfamily and function as ligand-dependent transcription factors that regulate cholesterol homeostasis, lipid homeostasis, and immune responses. LXR antagonists are promising treatments for hypercholesterolemia and diabetes. However,...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Front Chem |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Frontiers Media S.A.
2021
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8187946/ https://ncbi.nlm.nih.gov/pubmed/34124002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2021.674967 |
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