Interactive Effects of Glucocorticoids and Cytochrome P450 Polymorphisms on the Plasma Trough Concentrations of Voriconazole

Aims: To explore the interactive influence of glucocorticoids and cytochrome P450 (CYP450) polymorphisms on voriconazole (VRC) plasma trough concentrations (C(min)) and provide a reliable basis for reasonable application of VRC. Methods: A total of 918 VRC C(min) from 231 patients was collected and...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Jia, Su-jie, Gao, Ke-qin, Huang, Pan-hao, Guo, Ren, Zuo, Xiao-cong, Xia, Qing, Hu, Shuang-yao, Yu, Zhen, Xie, Yue-liang
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185288/
https://ncbi.nlm.nih.gov/pubmed/34113252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.666296
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