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Inflammation Is Associated with Voriconazole Trough Concentrations

Voriconazole concentrations display a large variability, which cannot completely be explained by known factors. Inflammation may be a contributing factor, as inflammatory stimuli can change the activities and expression levels of cytochrome P450 isoenzymes. We explored the correlation between inflam...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: van Wanrooy, Marjolijn J. P., Span, Lambert F. R., Rodgers, Michael G. G., van den Heuvel, Edwin R., Uges, Donald R. A., van der Werf, Tjip S., Kosterink, Jos G. W., Alffenaar, Jan-Willem C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249508/
https://ncbi.nlm.nih.gov/pubmed/25223994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03820-14
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