Relationship between Trough Plasma and Epithelial Lining Fluid Concentrations of Voriconazole in Lung Transplant Recipients

Trough (predose) voriconazole concentrations in plasma and pulmonary epithelial lining fluid (ELF) of lung transplant recipients receiving oral voriconazole preemptive treatment were determined. The mean (± standard deviation [SD]) ELF/plasma ratio was 12.5 ± 6.3. A strong positive linear relationsh...

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Main Authors: Heng, Siow-Chin, Snell, Gregory I., Levvey, Bronwyn, Keating, Dominic, Westall, Glen P., Williams, Trevor J., Whitford, Helen, Nation, Roger L., Slavin, Monica A., Morrissey, Orla, Kong, David C. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754345/
https://ncbi.nlm.nih.gov/pubmed/23817382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00942-13
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