Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer

Despite advances in the development of highly effective androgen receptor (AR)-directed therapies for the treatment of men with advanced prostate cancer, acquired resistance to such therapies frequently ensues. A significant subset of patients with resistant disease develop AR-negative tumors that l...

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Publicado en:Nat Commun
Main Authors: Brady, Nicholas J., Bagadion, Alyssa M., Singh, Richa, Conteduca, Vincenza, Van Emmenis, Lucie, Arceci, Elisa, Pakula, Hubert, Carelli, Ryan, Khani, Francesca, Bakht, Martin, Sigouros, Michael, Bareja, Rohan, Sboner, Andrea, Elemento, Olivier, Tagawa, Scott, Nanus, David M., Loda, Massimo, Beltran, Himisha, Robinson, Brian, Rickman, David S.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8185096/
https://ncbi.nlm.nih.gov/pubmed/34099734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23780-y
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