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Generation of functional liver organoids on combining hepatocytes and cholangiocytes with hepatobiliary connections ex vivo
In the liver, the bile canaliculi of hepatocytes are connected to intrahepatic bile ducts lined with cholangiocytes, which remove cytotoxic bile from the liver tissue. Although liver organoids have been reported, it is not clear whether the functional connection between hepatocytes and cholangiocyte...
Zapisane w:
| Wydane w: | Nat Commun |
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| Główni autorzy: | , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group UK
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8185093/ https://ncbi.nlm.nih.gov/pubmed/34099675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23575-1 |
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