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Progressive induction of hepatocyte progenitor cells in chronically injured liver

Differentiated epithelial cells show substantial lineage plasticity upon severe tissue injuries. In chronically injured mouse livers, part of hepatocytes become Sry-HMG box containing 9 (Sox9) (+) epithelial cell adhesion molecule (−) hepatocyte nuclear factor 4 α (+) biphenotypic hepatocytes. Howev...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tanimizu, Naoki, Ichinohe, Norihisa, Yamamoto, Masahiro, Akiyama, Haruhiko, Nishikawa, Yuji, Mitaka, Toshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209740/
https://ncbi.nlm.nih.gov/pubmed/28051157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39990
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