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Progressive induction of hepatocyte progenitor cells in chronically injured liver

Differentiated epithelial cells show substantial lineage plasticity upon severe tissue injuries. In chronically injured mouse livers, part of hepatocytes become Sry-HMG box containing 9 (Sox9) (+) epithelial cell adhesion molecule (−) hepatocyte nuclear factor 4 α (+) biphenotypic hepatocytes. Howev...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Tanimizu, Naoki, Ichinohe, Norihisa, Yamamoto, Masahiro, Akiyama, Haruhiko, Nishikawa, Yuji, Mitaka, Toshihiro
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5209740/
https://ncbi.nlm.nih.gov/pubmed/28051157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39990
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