Extracellular vesicles containing miR-146a-5p secreted by bone marrow mesenchymal cells activate hepatocytic progenitors in regenerating rat livers

BACKGROUND: Small hepatocyte-like progenitor cells (SHPCs) appear to form transient clusters in rat livers treated with retrorsine (Ret) and 70% partial hepatectomy (PH). We previously reported that the expansion of SHPCs was amplified in Ret/PH-treated rat livers transplanted with Thy1(+) cells der...

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Publicado en:Stem Cell Res Ther
Main Authors: Ichinohe, Norihisa, Ishii, Masayuki, Tanimizu, Naoki, Mizuguchi, Toru, Yoshioka, Yusuke, Ochiya, Takahiro, Suzuki, Hiromu, Mitaka, Toshihiro
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2021
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8164814/
https://ncbi.nlm.nih.gov/pubmed/34051870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-021-02387-6
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