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Prolonged oxidative stress and delayed tissue repair exacerbate acetaminophen-induced liver injury in aged mice
The liver gradually loses its regenerative capabilities with aging. However, it remains unknown whether aging affects drug-induced liver injury. Here, we used acetaminophen induced acute liver injury model to compare tissue injury and regeneration of aged mice (>80 weeks old) with young ones (8–1...
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| Publicado no: | Aging (Albany NY) |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7732315/ https://ncbi.nlm.nih.gov/pubmed/33001859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103973 |
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