Cryo-EM structure of TFIIH/Rad4–Rad23–Rad33 in damaged DNA opening in nucleotide excision repair

The versatile nucleotide excision repair (NER) pathway initiates as the XPC–RAD23B–CETN2 complex first recognizes DNA lesions from the genomic DNA and recruits the general transcription factor complex, TFIIH, for subsequent lesion verification. Here, we present a cryo-EM structure of an NER initiati...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: van Eeuwen, Trevor, Shim, Yoonjung, Kim, Hee Jong, Zhao, Tingting, Basu, Shrabani, Garcia, Benjamin A., Kaplan, Craig D., Min, Jung-Hyun, Murakami, Kenji
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184850/
https://ncbi.nlm.nih.gov/pubmed/34099686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23684-x
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