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Inhibition of Excision of Oxidatively Generated Hydantoin DNA Lesions by NEIL1 by the Competitive Binding of the Nucleotide Excision Repair Factor XPC-RAD23B

The interplay between nucleotide excision repair (NER) and base excision repair (BER) of non-bulky, oxidatively generated DNA lesion, has long been a subject of significant interest. The hydantoin oxidation products of 8-oxoguanine, spiroiminodihydantoin (Sp) and 5-guanidinohydantoin (Gh), are subst...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Kolbanovskiy, Marina, Shim, Yoonjung, Min, Jung-Hyun, Geacintov, Nicholas E., Shafirovich, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7413705/
https://ncbi.nlm.nih.gov/pubmed/32302101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00080
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