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Inhibition of Excision of Oxidatively Generated Hydantoin DNA Lesions by NEIL1 by the Competitive Binding of the Nucleotide Excision Repair Factor XPC-RAD23B
The interplay between nucleotide excision repair (NER) and base excision repair (BER) of non-bulky, oxidatively generated DNA lesion, has long been a subject of significant interest. The hydantoin oxidation products of 8-oxoguanine, spiroiminodihydantoin (Sp) and 5-guanidinohydantoin (Gh), are subst...
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| Pubblicato in: | Biochemistry |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7413705/ https://ncbi.nlm.nih.gov/pubmed/32302101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00080 |
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