Cryo-EM structure of TFIIH/Rad4–Rad23–Rad33 in damaged DNA opening in nucleotide excision repair

The versatile nucleotide excision repair (NER) pathway initiates as the XPC–RAD23B–CETN2 complex first recognizes DNA lesions from the genomic DNA and recruits the general transcription factor complex, TFIIH, for subsequent lesion verification. Here, we present a cryo-EM structure of an NER initiati...

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Publicado en:Nat Commun
Autores principales: van Eeuwen, Trevor, Shim, Yoonjung, Kim, Hee Jong, Zhao, Tingting, Basu, Shrabani, Garcia, Benjamin A., Kaplan, Craig D., Min, Jung-Hyun, Murakami, Kenji
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184850/
https://ncbi.nlm.nih.gov/pubmed/34099686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23684-x
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