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Evolutionary Conservation of Structural and Functional Coupling between the BRM AT-Hook and Bromodomain

The BAF chromatin remodeling complex is critical for genome regulation. The central ATPase of BAF is either BRM or BRG1, both of which contain a C-terminal bromodomain, known to associate with acetylated lysines. We have recently demonstrated that in addition to acetyl-lysine binding, the BRG1/BRM b...

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Publicat a:J Mol Biol
Autors principals: Lupo, Brianna E., Chu, Peirou, Harms, Michael J., Morrison, Emma A., Musselman, Catherine A.
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184587/
https://ncbi.nlm.nih.gov/pubmed/33539881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2021.166845
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