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Evolutionary Plasticity of Protein Families: Coupling Between Sequence and Structure Variation

In this work we examine how protein structural changes are coupled with sequence variation in the course of evolution of a family of homologs. The sequence–structure correlation analysis performed on 81 homologous protein families shows that the majority of them exhibit statistically significant lin...

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Detalhes bibliográficos
Main Authors: Panchenko, Anna R., Wolf, Yuri I., Panchenko, Larisa A., Madej, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941674/
https://ncbi.nlm.nih.gov/pubmed/16184609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.20644
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