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The Molecular Basis of Specific DNA Binding by the BRG1 AT-hook and Bromodomain
The ATP-dependent BAF chromatin remodeling complex plays a critical role in gene regulation by modulating chromatin architecture, and is frequently mutated in cancer. Indeed, subunits of the BAF complex are found to be mutated in >20% of human tumors. The mechanism by which BAF properly navigates...
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| Publicado no: | Biochim Biophys Acta Gene Regul Mech |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7350285/ https://ncbi.nlm.nih.gov/pubmed/32376391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2020.194566 |
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