Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance

Mammalian SWI/SNF [also called Brg/Brahma-associated factors (BAFs)] are evolutionarily conserved chromatin-remodeling complexes regulating gene transcription programs during development and stem cell differentiation. BAF complexes contain an ATP (adenosine 5′-triphosphate)–driven remodeling enzyme...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Fedorov, Oleg, Castex, Josefina, Tallant, Cynthia, Owen, Dafydd R., Martin, Sarah, Aldeghi, Matteo, Monteiro, Octovia, Filippakopoulos, Panagis, Picaud, Sarah, Trzupek, John D., Gerstenberger, Brian S., Bountra, Chas, Willmann, Dominica, Wells, Christopher, Philpott, Martin, Rogers, Catherine, Biggin, Philip C., Brennan, Paul E., Bunnage, Mark E., Schüle, Roland, Günther, Thomas, Knapp, Stefan, Müller, Susanne
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4681344/
https://ncbi.nlm.nih.gov/pubmed/26702435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500723
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