The Molecular Basis of Specific DNA Binding by the BRG1 AT-hook and Bromodomain

The ATP-dependent BAF chromatin remodeling complex plays a critical role in gene regulation by modulating chromatin architecture, and is frequently mutated in cancer. Indeed, subunits of the BAF complex are found to be mutated in >20% of human tumors. The mechanism by which BAF properly navigates...

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Bibliografski detalji
Izdano u:Biochim Biophys Acta Gene Regul Mech
Glavni autori: Sanchez, Julio C., Zhang, Liyang, Evoli, Stefania, Schnicker, Nicholas J., Nunez-Hernandez, Maria, Yu, Liping, Wereszczynski, Jeff, Pufall, Miles A., Musselman, Catherine A.
Format: Artigo
Jezik:Inglês
Izdano: 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7350285/
https://ncbi.nlm.nih.gov/pubmed/32376391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2020.194566
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